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Taltirelin acetate

CAS No. 1549593-23-8

Taltirelin acetate( TA-0910 acetate )

Catalog No. M22365 CAS No. 1549593-23-8

Taltirelin acetate is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 69 Get Quote
25MG 143 Get Quote
50MG 284 Get Quote
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Biological Information

  • Product Name
    Taltirelin acetate
  • Note
    Research use only, not for human use.
  • Brief Description
    Taltirelin acetate is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).
  • Description
    Taltirelin acetate is a superagonist at thyrotropin-releasing hormone receptor (TRH-R)(IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release)).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    TA-0910 acetate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    THR
  • Research Area
    Nervous system
  • Indication
    Spinocerebellar Degeneration

Chemical Information

  • CAS Number
    1549593-23-8
  • Formula Weight
    465.46
  • Molecular Formula
    C19H27N7O7
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (268.55 mM; Need ultrasonic)
  • SMILES
    O=C(N(CCC1)[C@@H]1C(N)=O)[C@@H](NC([C@@H](NC2=O)CC(N2C)=O)=O)CC3=CN=CN3.CC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Thirunarayanan N, et al. Taltirelin is a superagonist at the human thyrotropin-releasing hormone receptor. Front Endocrinol (Lausanne). 2012 Oct 9;3:120.
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